HBHI is excited to announce the results of our inaugural Truveta RFP Pilot season. We received over 40 applications from across Johns Hopkins University and have awarded funding for 25 Phase One pilot projects. These Phase One projects are designed to test feasibility, refine research questions, and build the foundation for larger studies. Congratulations to the awardees, and thank you to all applicants for their innovative proposals.

Phase Two awards, providing up to $25,000 for expanded data access and research support, are due September 15.

Population-Level Outcomes of Rituximab Therapy in ANCA-Associated Vasculitis

PIs: Brendan Antiochos, MD - JHU/SOM; Duvuru Geetha, MD - JHU/SOM; Brendan Denvir, MD - JHU/SOM

Real-World Effectiveness and Economics of Semaglutide and Tirzepatide versus Metformin for Antipsychotic-Induced Weight Gain

PIs: Ariana Marie Chao, PhD, JHU/SOM and SON; Eric Slade, PhD - JHU/SON and BSPH; Gail Daumit, MD, MHS - JHU/SOM; Jiayi Tong, PhD - JHU/BSPH; Joseph Levy, PhD - JHU/BSPH

Evaluating Inequities in Platelet Transfusion Practices Across Patient Demographics and Institutions

PI: David Daniel, MD - JHU/SOM; Elizabeth P. Crowe, MD, PhD - JHU/SOM; Ruchika Goel, MD, MPH - Southern Illinois University

Food allergy and omalizumab

PI: Jennifer Dantzer, MD - JHU/SOM

Investigating Maternal Health in the Telehealth Era: Can IT Alleviate the Maternal Health Crisis?

PI: Atiye Cansu Erol, PhD - JHU/Carey Business School

Adoption and Discontinuation of Lecanemab Among US Adults with Alzheimer’s Disease

PI: Ravi Gupta, MD - JHU/SOM

A real-world data-informed approach to optimize telehealth care for cancer patients

PI: Elham Hatef, MD, MPH - JHU/SOM and BSPH

Weight Changes from Continued Use and Discontinuation of Glucagon-Like Peptide-1 Agonists (GLP-1s)

PIs: Hemalkumar B. Mehta, PhD, MS - JHU/BSPH; Yizhen Xu, PhD - University of Utah/SOM; Scott Zeger, PhD, MS - JHU/BSPH and SOM; G. Caleb Alexander, MD, MS - JHU/BSPH

Leveraging Truveta Data to Distinguish Between Transfemoral and Transcarotid Artery Stenting

PIs: Caitlin Hicks, MD, MS - JHU/SOM; Jesse Columbo, MD - Dartmouth Hitchcock Medical Center; Chen Dun, PhD Candidate - JHU/SOM; David P. Stonko, MD, MS - JHH

Understanding Gaps in Emergency Care for Older Adults: A Data-Driven Analysis to Identify Opportunities for AI-Driven Decision Support

PIs: Eili Klein, MA, PhD - JHU/SOM; Jeremiah Hinson, MD, MPH - JHU/SOM; Phillip Magidson, MD, MPH - JHU/SOM; Martin Copenhaver, PhD - JHU/SOM

Fungal sepsis and anti-fungals

PIs: Theodore J Iwashyna, MD, PhD - Bloomberg Distinguished Professor - JHU/SOM and BSPH; Robert John Flick, MD - JHU/SOM

Establishing an Analytic Powerhouse for Risk Prediction Models in Nationwide Clinical Data

PI: Kunihiro Matsushita, MD, PhD - JHU/BSPH & SOM

Assessing Implications of the Credence Property in Treatment Decisions

PIs: Seth Richards-Shubik, PhD - JHU/KSAS; Efrat Armon, PhD Candidate - JHU/KSAS; Michael Darden, PhD; JHU/Carey Business School

Identifying Family Caregivers in the EMR of 3 Serious Illness Populations

PIs: Martha Abshire Saylor, PhD, RN - JHU/SON; Kathy McDonald, PhD, MM, BS - JHU/SON and BSPH; Katherine A. Ornstein, PhD, MPH - JHU/SON; Kelly Therese Gleason, PhD, MPH - JHU/SON

Leveraging Electronic Health Records to Detect and Respond to Xylazine as an Emerging Drug Threat

PIs: Olivia K. Sugarman, PhD, MPH - JHU/BSPH; Matthew Eisenberg, PhD - JHU/BSPH; Sachini Bandara, PhD, MS - JHU/BSPH; Samantha J. Harris, PhD, MPA - JHU/BSPH

Using Truveta’s Electronic Health Records and Claims Data to Study Early-Onset Dementia

PI: Kali Thomas, PhD, MA, BA - JHU/SON and BSPH

Investigating medicinal cannabis use and its health effects in Truveta EHR data

PIs: Johannes Thrul, PhD, MS - JHU/BSPH & SOM; Ryan Vandrey, PhD - JHU/SOM; Paul Nagy, PhD - JHU/SOM; Mark Dredze, PhD - JHU/WSE

Physician Teamwork and Specialization in Health Care

PI: Nicholas Tlipman, PhD - JHU/Carey Business School

Temporal Trends and Physician Prescribing Patterns of GLP-1 Receptor Agonists: A Real-World Multi-Site Analysis from 2018 to 2024 with Truveta Data

PIs: Emilia Simeonova, PhD - JHU/Carey Business School; Jiayi Tong, PhD - JHU/BSPH

Examining Treatment Received by Patients Following Prior Authorization Requests in Medicare Advantage

PIs: Jianhui (Frank) Xu, PhD - JHU/BSPH; Kelly Anderson, PhD, MPP - JHU/BSPH; Amit Jain, MD, MBA - JHU/SOM; Dan Polsky, PhD - Bloomberg Distinguished Professor, JHU/BSPH, Carey Business School, SON & SOM

ADRD / Mgmt Chronic Conditions / Tech Info

PIs: Dan Polsky, PhD - Bloomberg Distinguished Professor, JHU/BSPH, Carey Business School, SON & SOM; Zhang Zhang, PhD - JHU/BSPH; Nancy Schoenborn, MD - JHU/SOM

Patterns in healthcare utilization before and after a suicidal event at Emergency Departments

PI: Matthew Eisenberg, PhD - JHU/BSPH

Endogenous Cancer Screening and Health Behaviors

PIs: Michael Darden, PhD - JHU/Carey Business School; Alex Hoagland, PhD - University of Toronto/SPH

Financial Toxicity in Cancer Patients

PIs: Leila Mady, MD, PhD, MPH - JHU/SOM; Sudip Gupta, PhD - JHU/Carey Business School

OUD Testing

PI: Brendan Saloner, PhD - JHU/BSPH